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Refractory pulmonary artery aneurysm in Behçet's disease
Dong Xie1, Chang Chen1, Haifeng Wang1
11 Department of Thoracic and Cardiovascular Surgery, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China ; 2 Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
Annals of Translational Medicine
|November 6, 2015
Summary
Pulmonary artery aneurysms (PAA) in Behçet's disease (BD) can cause severe bleeding. This study presents a novel endovascular occlusion and salvage pneumonectomy approach for a refractory case, proposing a new treatment algorithm.
Area of Science:
- Vascular Surgery
- Cardiology
- Rheumatology
Background:
- Pulmonary artery aneurysms (PAA) are a rare but serious complication of Behçet's disease (BD).
- Massive hemoptysis from PAAs necessitates urgent intervention, often surgical or endovascular.
- Current therapeutic strategies and algorithms for managing PAAs in BD are lacking, particularly for the main pulmonary artery trunk.
Purpose of the Study:
- To report a novel endovascular occlusion technique for a refractory right main pulmonary artery aneurysm in a Behçet's disease patient.
- To describe a subsequent salvage pneumonectomy procedure.
- To propose a therapeutic algorithm for managing pulmonary artery aneurysms in Behçet's disease.
Main Methods:
- A case of Behçet's disease with a refractory right main pulmonary artery aneurysm presenting with massive hemoptysis was treated.
- The patient underwent an initial endovascular occlusion procedure.
- A salvage right pneumonectomy was performed due to persistent symptoms.
Main Results:
- Successful endovascular occlusion of the right main pulmonary artery aneurysm was achieved.
- A salvage pneumonectomy was performed successfully.
- The proposed therapeutic algorithm aims to guide management of this rare condition.
Conclusions:
- Endovascular occlusion combined with salvage pneumonectomy can be a viable treatment option for refractory pulmonary artery aneurysms in Behçet's disease.
- The proposed algorithm offers a structured approach to managing these complex cases.
- Further research is needed to validate the proposed algorithm and explore long-term outcomes.
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