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Updated: Mar 30, 2026

Author Spotlight: Point-of-Care Ultrasound for Gastric Content Assessment and Risk Stratification in Perioperative Care
Published on: September 22, 2023
[Proton pump inhibitors (PPI): may be not as harmless as believed]
Proton pump inhibitors (PPIs) are widely used for acid reflux but long-term use may cause side effects. This review examines known and potential risks associated with prolonged PPI therapy.
Area of Science:
- Gastroenterology
- Pharmacology
Context:
- Proton pump inhibitors (PPIs) are frequently prescribed globally.
- Increasing PPI usage necessitates understanding long-term implications.
Purpose:
- To review the established and potential long-term adverse effects of PPIs.
- To address growing concerns regarding the safety of prolonged PPI use.
Summary:
- PPIs demonstrate efficacy and good short-term tolerance with reversible side effects.
- Evidence is mounting regarding potential risks associated with extended PPI treatment.
Impact:
- Informing clinical practice regarding judicious PPI prescribing.
- Guiding patient counseling on the risks versus benefits of long-term PPI therapy.
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