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Randomized controlled trial comparing laparoscopic greater curvature plication versus laparoscopic sleeve gastrectomy
V V Grubnik1,2,3, O B Ospanov4,5, K A Namaeva4
1Department of Surgery, Odessa National Medical University, Odessa, Ukraine. uamelt@gmail.com.
Surgical Endoscopy
|November 7, 2015
Summary
Laparoscopic sleeve gastrectomy (LSG) shows superior long-term weight loss results compared to laparoscopic greater curvature plication (LGCP). LGCP is less effective for sustained weight management post-bariatric surgery.
Area of Science:
- Bariatric surgery
- Minimally invasive procedures
- Obesity management
Background:
- Laparoscopic greater curvature plication (LGCP) is a novel restrictive bariatric procedure.
- LGCP shares a restrictive mechanism with laparoscopic sleeve gastrectomy (LSG) but aims to avoid leak risks.
Purpose of the Study:
- To compare the 2-year outcomes of LSG and LGCP.
- Evaluate the efficacy of LGCP versus LSG in morbidly obese patients.
Main Methods:
- A multicenter prospective randomized trial involving 54 morbidly obese patients.
- Patients were allocated to either LGCP (n=25) or LSG (n=27) groups.
- Data collected included operative time, complications, hospital stay, BMI loss, %EWL, appetite, and comorbidity improvement.
Main Results:
- No significant differences in operative time or hospital stay between LSG and LGCP.
- After 2 years, LSG achieved significantly higher %EWL (78.9%) compared to LGCP (42.4%).
- LSG also led to a greater reduction in hunger (76.9%) versus LGCP (25%) after 2 years, with both procedures improving comorbidities.
Conclusions:
- Short-term outcomes showed similar effectiveness for both procedures.
- Long-term follow-up (2 years) indicated that LGCP is less effective than LSG for weight loss.
- LSG is a more effective restrictive bariatric procedure for sustained weight loss compared to LGCP.

