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Updated: Aug 7, 2026

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
09:33

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

Published on: February 7, 2015

Carotid Artery Longitudinal Displacement, Cardiovascular Disease and Risk Factors: The Multi-Ethnic Study of

Adam D Gepner1, Laura A Colangelo2, Nicole Reilly1

  • 1Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.

Plos One
|November 7, 2015
PubMed

Insights

Carotid artery longitudinal displacement, a measure of artery movement, is linked to ethnicity and intima-media thickness. This displacement may help predict cardiovascular disease and coronary heart disease events.

Area of Science:

  • Cardiovascular Science
  • Vascular Biology
  • Medical Imaging

Background:

  • Investigated associations between carotid artery longitudinal displacement, cardiovascular disease (CVD) risk factors, and CVD events.
  • Utilized a large, multi-ethnic cohort for comprehensive analysis.

Purpose of the Study:

  • To evaluate the relationship between carotid artery longitudinal displacement and CVD risk.
  • To determine if longitudinal displacement can predict future CVD and coronary heart disease (CHD) events.

Main Methods:

  • Developed a novel ultrasound speckle-tracking protocol to measure carotid artery longitudinal displacement.
  • Analyzed data from 389 participants in the Multi-Ethnic Study of Atherosclerosis.
  • Employed univariate analyses, Pearson correlations, and Cox proportional hazards models.

Main Results:

  • Less longitudinal displacement was associated with Chinese ethnicity compared to White.
  • Greater longitudinal displacement correlated with increased carotid intima-media thickness.
  • Longitudinal displacement showed a trend towards predicting CHD and CVD events, though not statistically significant.

Conclusions:

  • Carotid artery longitudinal displacement is associated with ethnicity and carotid intima-media thickness.
  • Longitudinal displacement may serve as a potential predictor for adverse cardiovascular and coronary heart disease events.
Abstract

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