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Application of Aptamers in Histopathology
Sarah Shigdar1, Li Lv2, Lifen Wang3
1School of Medicine, Deakin University, Waurn Ponds, VIC, 3216, Australia.
Methods in Molecular Biology (Clifton, N.J.)
|November 11, 2015
Abstract:
Aptamers are proving to be exceedingly effective in a number of applications. Given the disadvantages of antibodies, such as batch-to-batch variation and cross-reactivity, aptamers have the potential to revolutionize the field of histopathology due to their high specificity and the ease of their synthesis and modification. Here, we describe a chromogenic staining method for paraffin-embedded tissue sections with FITC-labeled aptamers.
