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Effect of intravaginal dehydroepiandrosterone treatment on the endometrium: should androstenediol be a concern?

Frank Z Stanczyk1

  • 1Keck School of Medicine University of Southern California Los Angeles, California.

Menopause (New York, N.Y.)
|November 12, 2015
PubMed
Abstract

No abstract available in PubMed .

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Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
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