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Out of the Mouth of Minnows
Matthew P Harris1, M Brent Hawkins2
1Department of Genetics, Harvard Medical School, Orthopaedic Research Laboratories, Boston Children's Hospital, 300 Longwood Avenue Enders 260, Mail Stop 3096, Boston, MA 02115, USA.
Abstract:
The skeleton articulates at specialized junctions, or joints. Although many factors that specify joints are known, how these different mechanisms are integrated to define the joint remains unclear. In this issue of Developmental Cell, Askary et al. (2015) utilize zebrafish to identify genetic regulatory mechanisms of joint specification and differentiation.
