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Immune function of Chinese formula Qingwen Baidu granule in broilers
Shijin Guo1, Shijun Fu1, Qianqian Xu1
1Shandong Binzhou Animal Science and Veterinary Medicine Academy, Shandong, China.
Central-European Journal of Immunology
|November 12, 2015
Summary
Qingwen Baidu granules enhance broiler immunity by boosting antibody levels against Newcastle Disease and improving immune organ development. This study shows significant improvements in both cellular and humoral immunity in chickens.
Area of Science:
- Veterinary Immunology
- Poultry Science
- Pharmacology
Background:
- Broiler immunity is crucial for disease prevention and productivity.
- Assessing the impact of herbal preparations on poultry immune systems is an area of interest.
- Newcastle Disease remains a significant threat to poultry health.
Purpose of the Study:
- To investigate the effects of Qingwen Baidu granules on broiler immunity.
- To evaluate the impact on antibody levels, immune organ indices, and lymphocyte transformation.
- To determine the efficacy of Qingwen Baidu granules in enhancing chicken immune function.
Main Methods:
- Hy-line variety white cocks (30 days old) were used.
- Antibody titers for Newcastle Disease were measured.
- MTT assay determined T lymphocyte proliferation.
- Immune organ indices (bursa, thymus, spleen) were measured via organ weighing.
Main Results:
- Qingwen Baidu granules prolonged residue time and improved lymphocyte conversion ratio.
- Significant increases in bursa, thymus, and spleen indices were observed.
- Enhanced immune organ development and growth were noted.
Conclusions:
- Qingwen Baidu granules improve serum antibody levels and peripheral blood lymphocyte proliferation.
- The granules enhance cellular immune function and elevate immune organ indices.
- Qingwen Baidu granules effectively potentiate both cytoimmunity and humoral immunity in broilers.
