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Predictors of Third Molar Impaction: A Systematic Review and Meta-analysis.
1Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA carter@fas.harvard.edu.
Journal of Dental Research
|November 13, 2015
Summary
This meta-analysis found a worldwide third molar (M3) impaction prevalence of 24.40% in adults. Mandibular impactions were more common than maxillary, with no significant sex difference observed.
Area of Science:
- Dentistry
- Oral Surgery
- Public Health
Background:
- Third molar (M3) impaction is a common dental issue.
- Understanding its global prevalence is crucial for public health planning and resource allocation.
- Previous estimates vary, necessitating a comprehensive meta-analysis.
Purpose of the Study:
- To conduct a meta-analysis evaluating the global prevalence of third molar (M3) impaction.
- To analyze impaction prevalence based on location (mandible vs. maxilla), sex, impaction angle, and number of impacted M3s.
- To identify potential biases and limitations in existing M3 impaction research.
Main Methods:
- A systematic literature search was performed across PubMed, ISI Web of Science, and Google Scholar.
- Included studies reported M3 impaction prevalence from radiographic examinations in individuals aged 17 years and older.
- Risk of bias was assessed, and data from 49 studies involving 83,484 individuals were analyzed.
Main Results:
- The overall worldwide prevalence of M3 impaction was 24.40%.
- Mandibular M3 impaction was significantly more common than maxillary impaction (odds ratio > 1).
- Mesioangular impaction was the most frequent type, and impaction of one or two M3s was more common than three or four.
Conclusions:
- The global prevalence of third molar impaction is 24.40%, which is lower than some previous estimates.
- While mandibular impactions are more prevalent, there is no significant difference in impaction rates between sexes.
- The findings highlight the need for careful consideration of M3 impaction prevalence in clinical practice and public health strategies.

