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[Erythema palmare hereditarium (Lane's disease): Report of a paediatric case]
M Durieux-Verde1, D Raffin2, C Dannepond1
1Université François-Rabelais de Tours, 60, rue du Plat-d'Étain, 37000 Tours, France; Unité de dermatologie pédiatrique, service de dermatologie, CHRU de Tours, avenue de la République, 37044 Tours cedex 9, France.
Background:
Palmar erythema may be either congenital or acquired, hereditary or non-hereditary. Its diagnosis and management differs according to whether or not it is acquired, hereditary or associated with symptoms. Herein, we report the case of a child with hereditary palmoplantar erythema (Lane's disease).
Observation:
A 2½-year-old girl consulted for palmar erythema, present since birth, predominantly on the thenar and hypothenar eminences and on the palmar aspect of her fingers. She also presented mild diffuse erythema on the soles of her feet. Both her mother and grandmother had similar signs. The girl had neither impairment nor pain linked to this erythema, and she had no associated symptoms. Physical examination was otherwise normal, as were the results of standard laboratory tests.
Discussion:
We diagnosed Lane's disease based on the girl's hereditary erythema with autosomal dominant transmission, and the congenital and asymptomatic nature of her palmoplantar erythema. Nine publications have reported cases of Lane's disease, but this condition is probably highly under-reported.
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