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Computerized System for Staging Peritoneal Surface Malignancies.

Paolo Sammartino1, Daniele Biacchi2, Tommaso Cornali2

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A new digital staging system improves accuracy for peritoneal surface malignancies (PSMs) by providing detailed anatomic models for Peritoneal Cancer Index (PCI) and completeness of cytoreduction score (CC-s) calculations.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Medical Informatics

Background:

  • Peritoneal surface malignancies (PSMs) staging relies on Peritoneal Cancer Index (PCI) and completeness of cytoreduction score (CC-s).
  • Current staging methods lack detailed anatomic information, leading to laborious and unreliable assessments.
  • Accurate staging is crucial for patient selection and outcome evaluation in cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC).

Purpose of the Study:

  • To develop a computerized digital tool for staging PSMs.
  • To create a new anatomic scheme for calculating PCI and CC-s that reflects patient anatomy more accurately.
  • To integrate this tool into a web-based application for comprehensive PSM data management.

Main Methods:

  • Development of a digital tool featuring male and female anatomic models of 13 endoabdominal regions with defined anatomic landmarks.
  • Implementation of a drag-and-drop interface for computing PCI and CC-s.
  • Inclusion of features for localizing and quantifying disease pre- and post-treatment.

Main Results:

  • The digital tool provides a more accurate representation of patient anatomy for staging.
  • It simplifies the localization and quantification of disease burden.
  • Facilitates comparison of pre- and post-operative PCI, aiding in patient selection for CRS plus HIPEC.

Conclusions:

  • The computerized application offers a modern, user-friendly PSM staging system.
  • Its anatomic features and drag-and-drop functionality enhance staging accuracy and comparability.
  • The tool aids in stratifying patients into outcome classes based on residual disease after CRS plus HIPEC.