Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Infectious Diseases and Their Occurrence

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...

Inhibitors of Viral Protein Synthesis

Inhibitors of Viral Protein Synthesis

Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Selection and use of reference panels: a case study highlighting current gaps in the materials available for foot and mouth disease.

Revue scientifique et technique (International Office of Epizootics)·2021

Same author

Dynamics and risk of transmission of bovine tuberculosis in the emerging dairy regions of Ethiopia.

Epidemiology and infection·2021

Same author

Experimental evidence of mechanical lumpy skin disease virus transmission by Stomoxys calcitrans biting flies and Haematopota spp. horseflies.

Scientific reports·2019

Same author

Field observations and experiences gained from the implementation of control measures against lumpy skin disease in South-East Europe between 2015 and 2017.

Preventive veterinary medicine·2018

Same author

Preparedness activities and research needs in addressing emerging infectious animal and zoonotic diseases.

Revue scientifique et technique (International Office of Epizootics)·2018

Same author

Development and validation of a foot-and-mouth disease virus SAT serotype-specific 3ABC assay to differentiate infected from vaccinated animals.

Journal of virological methods·2018

Same journal

Development of a High-Resolution Melting (HRM)-Based Multiplex Real-Time PCR Assay of PEDV, TGEV, PoRV, PDCoV, PRV, and PRRSV.

Transboundary and emerging diseases·2026

Same journal

Infection of the Conceptus With African Swine Fever Virus Following Artificial Insemination in Sows: A Pathological Study.

Transboundary and emerging diseases·2026

Same journal

The PCK2-Traf6-Tollip Axis Restricts PEDV Replication by Orchestrating Selective Autophagic Degradation of the Viral Nucleocapsid Protein.

Transboundary and emerging diseases·2026

Same journal

Development and Application of a Blocking ELISA for the Detection of Feline Calicivirus Antibodies Based on Monoclonal Antibodies Against VP1 Protein.

Transboundary and emerging diseases·2026

Same journal

Celastrol Suppresses Porcine Deltacoronavirus Replication by Modulating Endoplasmic Reticulum Stress-Associated Ca<sup>2+</sup> Balance.

Transboundary and emerging diseases·2026

Same journal

Development of a Serotyping Scheme for Streptococcus pasteurianus: An Underreported Zoonotic Pathogen.

Transboundary and emerging diseases·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 30, 2026

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

Review: Capripoxvirus Diseases: Current Status and Opportunities for Control.

E S M Tuppurainen¹, E H Venter², J L Shisler³

¹Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

Transboundary and Emerging Diseases

|November 14, 2015

Summary

This summary is machine-generated.

Lumpy skin disease, sheeppox, and goatpox severely impact livestock. This review examines capripoxvirus control, vaccine efficacy, and future needs for disease eradication in farming industries.

Keywords:

control goatpox immunity lumpy skin disease sheeppox vaccines

More Related Videos

Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection

Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection

Published on: May 24, 2020

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

Published on: May 5, 2014

Related Experiment Videos

Last Updated: Mar 30, 2026

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection

Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection

Published on: May 24, 2020

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

Published on: May 5, 2014

Area of Science:

Veterinary Virology
Epizootiology
Immunology

Background:

Lumpy skin disease, sheeppox, and goatpox are significant capripoxvirus (CPXV) infections impacting domestic ruminants.
These diseases cause substantial economic losses in cattle, sheep, and goat farming, particularly in endemic areas.

Purpose of the Study:

To review the current geographical distribution, economic impact, epidemiology, transmission, and immunity of CPXV.
To scrutinize available vaccines, identify resource needs, and challenges for disease control and eradication.
To discuss progress in developing safer, more effective vaccines and their field evaluation.

Main Methods:

Literature review of CPXV epidemiology, transmission, and immunity.
Analysis of current vaccine strategies, including field efficacy.
Examination of genomic databases for poxviruses.

Main Results:

CPXV poses a high impact on livestock industries globally.
Current vaccines face challenges in efficacy and resource allocation for widespread control.
Genomic data offers potential for improved vaccine development.

Conclusions:

Effective CPXV control requires addressing challenges in vaccine accessibility and efficacy.
Further research into novel vaccine technologies and genomic insights is crucial for eradication efforts.
Integrated strategies are needed to mitigate the economic impact of these devastating ruminant diseases.