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Published on: September 5, 2017
Treatment of childhood tuberculosis in India
1Department of Health Research.
Insights
India
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- India bears a significant portion of the global tuberculosis (TB) burden, placing children at high risk.
- The Revised National Tuberculosis Control Programme (RNTCP) offers free diagnosis and treatment for pediatric TB.
- Recent guideline revisions aim to improve TB care for children in India.
Purpose of the Study:
- To outline the current strategies and recent updates in India's national TB control program for children.
- To highlight key areas for improvement in pediatric TB management and prevention.
- To inform stakeholders about the evolving landscape of TB control in Indian children.
Main Methods:
- Review of India's Revised National Tuberculosis Control Programme guidelines and practices.
- Analysis of diagnostic algorithms and treatment regimens for pediatric TB.
- Examination of active case-finding strategies and preventive therapy approaches.
Main Results:
- Updated diagnostic approaches and a shift to daily fixed-dose combination (FDC) pills with WHO-recommended dosages.
- Active case finding implemented in high-risk populations, including TB patient households, HIV-infected, and malnourished children.
- Emphasis on strengthening TB case notification and adherence to Standards of TB Care in the private sector.
Conclusions:
- India's RNTCP is implementing child-friendly, daily regimens and updated diagnostics for pediatric TB.
- Enhanced focus is needed on preventive therapy for young contacts and multidrug-resistant TB detection in children.
- Strengthening private sector engagement is crucial for comprehensive TB control in children.
Abstract:
With a quarter of the global burden of tuberculosis (TB) occurring in India, children in this country are at high risk of tuberculous infection and TB disease. India's Revised National Tuberculosis Control Programme provides free diagnosis and treatment for children with TB using quality assured, weight-based individual drug boxes. Guidelines have recently been revised, updating both the diagnostic algorithm and shifting to a daily regimen with World Health Organization recommended dosages using child-friendly, fixed-dose combination pills. Active case finding is practised in households of TB patients as well as among human immunodeficiency virus infected and malnourished children. More attention needs to be paid to the provision of preventive therapy for household contacts aged <6 years as well as to the detection of multidrug-resistant TB among children. Case notification and the use of the Standards of TB Care in India are being strengthened in the private sector.
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