Related Experiment Video
Updated: Mar 30, 2026
Non-thermal Infrared Light Treatment of Ischemia/Reperfusion Injury and Subsequent Analysis of Macrophage Differentiation
Published on: December 30, 2021
Remote ischemic preconditioning enhances fracture healing
Mehmet Faruk Çatma1, Hakan Şeşen2, Aytekin Aydın1
1Departments of Orthopaedics and Traumatology, Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey.
Purpose:
We hypothesized that RIP accelerates fracture healing.
Methods:
Rats (n = 48) were used for the technique of ischemic preconditioning involved applying 35 min of intermittent pneumatic tourniquet for 7 cycles of 5 min each to the fractured hind limb.
Results:
We observed greater callus maturity in RIP group at first week after fracture when compared to controls (p < 0,0001). The serum MDA levels demonstrated statistically lower values at the RIP group at the first week after fracture; however, there were not significant differences at 3rd and 5th weeks (p = 0.0001, p = 0.725, p = 0.271, respectively).
Conclusions:
Greater callus maturity was obtained in RIP group.
