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Updated: Dec 28, 2025

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
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Nutrition for Sarcopenia.

Hidekatsu Yanai1

  • 1Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, 1-7-1 Kohnodai, Chiba 272-8516, Japan.

Journal of Clinical Medicine Research
|November 14, 2015
PubMed
Summary

Nutritional interventions can help prevent age-related sarcopenia, characterized by muscle loss. Optimal protein intake (1.0-1.2 g/kg/day) and supplements like vitamin D show promise for improving muscle health in older adults.

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Area of Science:

  • Gerontology
  • Nutritional Science
  • Muscle Physiology

Background:

  • Aging-related sarcopenia involves decline in muscle mass, strength, and function.
  • Malnutrition is a significant factor associated with sarcopenia.
  • Metabolic factors in obesity and diabetes can accelerate sarcopenia progression.

Purpose of the Study:

  • To review the impact of nutritional factors on sarcopenia in the elderly.
  • To identify effective nutritional strategies for sarcopenia prevention and management.

Main Methods:

  • Systematic review of published articles on nutritional interventions for sarcopenia.
  • Analysis of evidence regarding protein intake, supplementation, and other dietary factors.

Main Results:

Keywords:
Beta-hydroxy-beta-methylbutyrateEnergy restrictionLeucineProtein intakeSarcopenia

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  • Optimal dietary protein intake recommended: 1.0-1.2 g/kg/day or 25-30g per meal.
  • Protein supplementation (cheese, milk protein, amino acids, vitamin D) shows potential.
  • Effectiveness and safety of caloric restriction for sarcopenia remain uncertain.

Conclusions:

  • Nutritional interventions are crucial for preventing age-related sarcopenia.
  • Adequate protein intake and targeted supplementation can improve muscle quality in the elderly.
  • Further research is needed on caloric restriction's role in sarcopenia.