[Cytotoxic antibodies to leukemia cells in normal human sera]

Antibodies cytotoxic for human leukemia cells were demonstrated in 7 parents of leukemia children and in 2 normal donors whose blood had induced a partial remission in leukemia and lymphoma patients. None of these sera were cytotoxic to remission cells nor to normal lymphocytes. These sera appear to be relatively specific for acute lymphoblastic leukemia cells; however, several antigenic specificities appear to be detected by these sera.