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Hemochromatosis
1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
This article discusses the pathophysiology and clinical manifestations of idiopathic and secondary hemochromatosis. Pedigree studies documenting the hereditary evidence for hemochromatosis are discussed. Current theories for the molecular mechanisms that result in iron overload are presented. Diagnostic strategies for assessing hemochromatosis and therapeutic modalities are reviewed.
This article discusses the pathophysiology and clinical manifestations of idiopathic and secondary hemochromatosis. Pedigree studies documenting the hereditary evidence for hemochromatosis are discussed. Current theories for the molecular mechanisms that result in iron overload are presented. Diagnostic strategies for assessing hemochromatosis and therapeutic modalities are reviewed.