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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Defining and recognising locally advanced basal cell carcinoma.

Jean Michel Amici1, Maxime Battistella1, Marie Beylot-Barry1

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Locally advanced basal cell carcinoma (laBCC) requires careful assessment. Experts developed a practical tool to analyze laBCC complexity by considering tumor, operability, and patient factors for better multidisciplinary decisions.

Keywords:
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Area of Science:

  • Dermatology
  • Oncology
  • Surgical Oncology

Background:

  • Basal cell carcinomas (BCCs) can rarely become extensively invasive and destructive.
  • This aggressive form is termed locally advanced BCC (laBCC).
  • Identifying diverse clinical settings of laBCC is crucial.

Purpose of the Study:

  • To define consensus on the characteristics of laBCC.
  • To develop a practical tool for assessing laBCC complexity.
  • To standardize multidisciplinary team (MDT) decisions for laBCC management.

Main Methods:

  • A panel of experts (oncodermatologists, surgeons, pathologists, radiotherapists, geriatricians) convened for a 1-day workshop.
  • Interactive discussions and case reviews were used to approach consensus.
  • A practical tool was developed based on identified assessment components.

Main Results:

  • Consensus was reached on the definition and assessment of laBCC through discussion of nine cases.
  • Three major components for laBCC assessment were identified: tumor factors, operability/procedure factors, and patient factors.
  • Competing risks of death were highlighted as critical for assessment.

Conclusions:

  • The developed grid serves as a method for analyzing laBCC complexity, not a definitive tool.
  • It aims to ensure homogeneous MDT decisions across various clinical settings.
  • This approach aids in managing complex laBCC cases.