Related Experiment Video
Updated: Mar 30, 2026

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
Published on: September 22, 2023
The sinonasal bacterial microbiome in health and disease
Vijay R Ramakrishnan1, Leah J Hauser, Daniel N Frank
1aDepartment of Otolaryngology, University of Colorado School of Medicine bDivision of Infectious Diseases cUniversity of Colorado Microbiome Research Consortium, Aurora, Colorado, USA.
Purpose Of Review:
The development of culture-independent bacterial DNA sequencing techniques and integration into research practice has led to a burgeoning interest in the microbiome and its relevance to human health and disease. Introduction into the study of chronic rhinosinusitis in the past few years has shaped current thinking on the role of bacteria in the disease process.
Recent Findings:
Rich and diverse populations of bacteria inhabit the sinonasal cavity at all times. Decreased bacterial richness and diversity may be associated with disease state and outcomes.
Summary:
Although there is much to be explored, the sinus microbiome appears to have potentially promising roles in many aspects of sinus health and disease.
More Related Videos
09:12Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
Published on: January 17, 2014
11:54Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
Published on: January 21, 2018
Related Concept Videos
Microbiota of the Respiratory Tract
The Oral Microbiota
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
Nose and Nasal Cavity
Microbiome of the Eye
Introduction to the Human Microbiota