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[Pathogen detection of 1 613 cases of hospitalized children with community acquired pneumonia]

Yi Peng1, Chang Shu, Zhou Fu

  • 1Deparment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. maggiechangshu@126.com.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|November 18, 2015
PubMed

Insights

Respiratory syncytial virus (RSV) and Hemophilus parainfluenzae are key pathogens causing community-acquired pneumonia (CAP) in Chongqing children. Mycoplasma pneumoniae (MP) is also significant, with frequent co-infections observed.

Area of Science:

  • Pediatric Infectious Diseases
  • Respiratory Medicine
  • Microbiology

Background:

  • Community-acquired pneumonia (CAP) is a significant cause of childhood illness.
  • Identifying causative pathogens is crucial for effective treatment and prevention strategies.
  • Understanding regional pathogen distribution is essential for public health initiatives.

Purpose of the Study:

  • To determine the prevalence and distribution of bacterial and viral pathogens in children diagnosed with CAP in the Chongqing region.
  • To investigate the role of Mycoplasma pneumoniae (MP) as a pathogen in pediatric CAP.
  • To assess the incidence of co-infections between bacteria and viruses in pediatric CAP cases.

Main Methods:

  • A cohort of 1,613 children with CAP in Chongqing was studied between January and December 2014.
  • Nasopharyngeal and blood specimens were collected for bacterial culture.
  • Detection of seven common respiratory viruses and antibodies against Mycoplasma pneumoniae (MP) were performed.

Main Results:

  • Bacterial pathogens were identified in 50.22% of cases, with Hemophilus parainfluenzae (40.8%), Streptococcus pneumoniae (29.7%), and Moraxella catarrhalis (7.3%) being most common.
  • Respiratory syncytial virus (RSV) was the most frequently detected virus (58.3%), followed by parainfluenza virus type 3 (17.4%) and adenovirus (14.3%).
  • Mycoplasma pneumoniae (MP) was detected in 29.82% of cases, and co-infections occurred in 32.18% of patients, with mixed bacterial and viral infections being prevalent (47.4%).

Conclusions:

  • Respiratory syncytial virus (RSV) and Hemophilus parainfluenzae are identified as the primary causative agents of community-acquired pneumonia in children from the Chongqing area.
  • Mycoplasma pneumoniae (MP) is also recognized as an important pathogen contributing to pediatric CAP.
  • The study highlights the high prevalence of co-infections involving both bacteria and viruses in children with CAP.
Abstract

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