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Circadian rhythms in liver metabolism and disease

Jessica M Ferrell1, John Y L Chiang1

  • 1Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown OH 44272, USA.

Acta Pharmaceutica Sinica. B
|November 19, 2015
PubMed

Keywords:
ARC, arcuate nucleusBMAL1, brain and muscle ARNT-like 1CAR, constitutive androstane receptorCLOCK, circadian locomotor output cycles kaputCRY, cryptochromeCYP7A1, cholesterol 7α-hydroxylaseCYPs, cytochrome P450 enzymesCircadian rhythmDBP, D-site binding proteinE-box, enhance boxEMT, emergency medical technicianFAA, food anticipatory activityFASPS, familial advanced sleep-phase syndromeFEO, food entrainable oscillatorFOXO3, forkhead box O3FXR, farnesoid-X receptorGLUT2, glucose transporter 2HDAC3, histone deacetylase 3HIP, hypoxia inducing proteinHLF, hepatic leukemia factorLDL, low-density lipoproteinLRH1, liver receptor homolog 1LiverMetabolic syndromeNAD+, nicotinamide adenine dinucleotidePER, periodRHT, retinohypothalamic tractRORE, ROR-response elementRORα, retinoid-related orphan receptor αSCN, suprachiasmatic nucleusSHP, small heterodimer partnerSIRT1, sirtuin 1TEF, thyrotroph embryonic factorTGR5, G protein-coupled bile acid receptorTTFL, transcriptional translational feedback loopType 2 diabetes

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