Emerging role of microRNAs in lipid metabolism

Zhihong Yang1, Tyler Cappello2, Li Wang3

  • 1Department of Physiology and Neurobiology, and the Institute for Systems Genomics, University of Connecticut, Storrs, CT 06269, USA ; Veterans Affairs Connecticut Healthcare System, West Haven, CT 06516, USA.

Keywords:
ABCA1, adenosine triphosphate-binding cassette transporter A1ABCG1, adenosine triphosphate-binding cassette transporter G1AMPKα, AMP-activated protein kinase αATP8B1, aminophospholipid transporter, class I, type 8B, member 1Ago2, argonaute 2ApoA1, apolipoprotein A1BDL, bile-duct ligationCPT1A, carnitine palmitoyltransferase 1ACRAT, carnitine O-acetyltransferaseCYP26, cytochrome P450 family 26CYP3A4, cytochrome P450 family 3 subfamily A polypeptide 4ERRγ, estrogen-related receptor gammaFABP7, fatty acid-binding protein 7FASN, fatty acid synthaseFGF21, fibroblast growth factor 21FGFR1, fibroblast growth factor receptor 1FXR, farnesoid X receptorGABPA, GA binding protein transcription factor alpha subunitGPC6, glypican 6HADHB, hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase trifunctional protein, beta subunitHCC, hepatocellular carcinomaHCV, hepatitis C virusHMGCR, 3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMGCS1, 3-hydroxy-3-methylglutaryl-coenzyme A synthase 1HNE, 4-hydroxynonenalIGF1R, insulin-like growth factor 1 receptorIGFBP3, insulin-like growth factor binding protein 3INSIG1, insulin induced gene 1LIPE, lipase hormone-sensitiveLNA, locked nucleic acidsLNPs, lipid-based nanoparticlesLPS, lipopolysaccharideLipid metabolismMED13, mediator complex subunit 13MHV68, murine γ-herpesvirus 68MTTP, microsomal TG transfer proteinNR1D1/REV-ERBα, transcriptional repressor nuclear receptor subfamily 1 group D member 1NRs, nuclear receptorsNuclear receptorsPCK1, phosphoenolpyruvate carboxykinase 1PDCD4, programmed cell death 4PGC-1, peroxisone proliferator-activated receptor gamma coactivatorPLIN1, perilipin 1PNA, peptide nucleic acidPNPLA2, patatin-like phospholipase domain containing 2PPARγ, peroxisone proliferator-activated receptor gammaRTL1, retrotransposon-like 1RXRα, retinoid X receptor alphaSHP, small heterodimer partnerSIRT1, sirtuin 1SIRT6, sirtuin 6TG, triglycerideTLR4, toll-like receptor 4miRNAs or miRs, microRNAsmicroRNAspre-miRNAs, precursor-miRNAspri-miRNAs, primary-miRNAs

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