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Updated: Mar 30, 2026

Visualization of the Superior Ocular Sulcus during Danio rerio Embryogenesis
Published on: March 27, 2019
BILATERAL OPTIC NERVE COLOBOMAS IN INFANT WITH TETRAPLOIDY
1*Department of Ophthalmology, University of Texas Health Science Center at San Antonio, San Antonio, Texas; and †Austin Retina Associates, Austin, Texas.
Purpose:
To describe the previously unreported ocular anomalies in the rare condition of tetraploidy.
Methods:
This study is a retrospective case report of a 23-day-old male infant with tetraploidy. RetCam fundus photography and neuroimaging were performed.
Results:
This 23-day-old male infant was born at full term and found to have tetraploidy with numerous congenital anomalies including bilateral optic nerve colobomas, left microphthalmia, vitreous hemorrhage, and septo-optic dysplasia.
Conclusion:
Infants with tetraploidy can present with ocular anomalies and while hospitalized should be examined by an ophthalmologist.
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