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Correlation Between Bladder Pain Syndrome/Interstitial Cystitis and Pelvic Inflammatory Disease
Shiu-Dong Chung1, Chao-Hsiang Chang, Peir-Haur Hung
1From the Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City (S-DC); School of Medicine, College of Medicine, Fu-Jen Catholic University, New Taipei (S-DC); Graduate Program in Biomedical Informatics, College of Informatics, Yuan Ze University (S-DC); Department of Urology, China Medical University and Hospital (C-HC); Department of Medicine, College of Medicine, China Medical University and Hospital, Taichung (C-HC, C-HM); Department of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi (P-HH); Department of Applied Life Science and Health, Chia-Nan University of Pharmacy and Science, Tainan (P-HH); Department of Health Risk Management, College of Public Health, China Medical University (C-JC); Department of Medical Research, China Medical University and Hospital (C-JC); Management Office for Health Data, China Medical University and Hospital, Taichung (C-HM); and Department of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan (C-YH).
Pelvic inflammatory disease (PID) is significantly more common in women with bladder pain syndrome/interstitial cystitis (BPS/IC). This population-based study found a strong correlation between these conditions, suggesting increased awareness is needed.
Area of Science:
- Urology
- Gynecology
- Epidemiology
Background:
- Pelvic inflammatory disease (PID) is linked to chronic pelvic pain and inflammation in Western studies.
- Bladder pain syndrome/interstitial cystitis (BPS/IC) is more prevalent in women, characterized by chronic pelvic pain and inflammation.
Purpose of the Study:
- To investigate the correlation between BPS/IC and PID using a population-based dataset.
- To determine if PID is a risk factor for BPS/IC or vice versa.
Main Methods:
- A case-control study was conducted using the Taiwan National Health Insurance program.
- 449 BPS/IC patients (cases) and 1796 controls were analyzed.
- Multivariate logistic regression estimated the association between BPS/IC and PID.
Main Results:
- PID prevalence was significantly higher in BPS/IC cases (41.7%) compared to controls (15.4%).
- The odds ratio for PID among BPS/IC cases was 3.69.
- Increased odds ratios for PID were observed across all age groups of BPS/IC patients.
Conclusions:
- A significant correlation exists between PID and BPS/IC.
- Clinicians should consider BPS/IC in women diagnosed with PID.
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