Building global capacity for brain and nervous system disorders research

Area of Science:

• Neuroscience
• Global Health
• Public Health Policy

Background:

• Neurological, neuropsychiatric, substance-use, and neurodevelopmental disorders pose a significant global health burden, particularly in low- and middle-income countries (LMICs).
• The impact of these disorders in LMICs is exacerbated by insufficient targeted research funding and a lack of in-country research capacity.
• Addressing these health issues effectively requires developing local research infrastructure and training skilled clinicians and scientists.

Purpose of the Study:

• To review the evolving issues, knowledge, and programs focused on building research capacity in LMICs.
• To specifically address the development of capacity for research on brain and nervous system disorders in these regions.

Main Methods:

• This review synthesizes information on existing challenges and successful strategies for research capacity building.
• It examines programs and initiatives aimed at strengthening individual, institutional, and national research capabilities.
• Focus is placed on the context of neurological, neuropsychiatric, substance-use, and neurodevelopmental disorders.

Main Results:

• Research capacity building in LMICs is essential for addressing the local burden of brain and nervous system disorders.
• Development of research infrastructure and training of local experts are key components for successful capacity building.
• Existing programs offer valuable insights into effective strategies for enhancing research capabilities in resource-limited settings.

Conclusions:

• Strengthening research capacity in LMICs is paramount to effectively manage and reduce the burden of neurological and mental health disorders.
• Investment in research infrastructure and human capital is critical for generating locally relevant evidence and informing policy.
• Collaborative efforts and targeted programs are necessary to build sustainable research capacity for brain and nervous system disorders in LMICs.