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Related Experiment Video

Updated: Mar 30, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
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Cellulitis and erysipelas: prevention.

Choon Chiat Oh1

  • 1Singapore General Hospital, Singapore, Republic of Singapore.

BMJ Clinical Evidence
|November 19, 2015
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Summary
This summary is machine-generated.

Preventing recurrent cellulitis (bacterial skin infection) and erysipelas involves evaluating antibiotic effectiveness and managing predisposing factors. This systematic overview categorizes interventions to guide clinical practice.

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Evidence-Based Medicine

Background:

  • Cellulitis is a common bacterial skin inflammation causing redness, pain, and potential systemic illness.
  • Erysipelas, a superficial form, often affects lower limbs and face, with streptococci and Staphylococcus aureus as common pathogens.
  • Recurrence affects approximately 25% of individuals within three years, necessitating preventive strategies.

Purpose of the Study:

  • To systematically review the effects of treatments aimed at preventing the recurrence of cellulitis and erysipelas.
  • To categorize the efficacy of interventions based on available evidence.

Main Methods:

  • A systematic overview was conducted, searching major databases including Medline, Embase, and The Cochrane Library up to February 2015.
  • A comprehensive search identified 323 studies, with 14 full publications undergoing detailed evaluation.
  • Evidence was appraised, including a GRADE evaluation for one PICO combination.

Main Results:

  • The overview identified and evaluated studies on the effectiveness and safety of various interventions.
  • Interventions were categorized based on their potential to prevent cellulitis and erysipelas recurrence.

Conclusions:

  • The systematic overview provides categorized efficacy for interventions targeting cellulitis and erysipelas recurrence.
  • Key interventions assessed include antibiotic therapy and the management of predisposing factors for these common skin infections.