Cardiac GR and MR: From Development to Pathology.

Rachel V Richardson1, Emma J Batchen2, Martin A Denvir2

  • 1Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK; Current address: Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle Upon Tyne, NE1 3BZ, UK.

Summary

Mineralocorticoid receptor (MR) antagonism treats heart failure. Glucocorticoid (GC) receptor (GR) also plays a key role in preventing heart disease, influencing cardiac health and disease.

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