Related Experiment Video
Updated: Jun 27, 2026

04:01
Revealing the Ferroptotic Phenotype of Medulloblastoma
Published on: March 15, 2024
HDL resuscitates cells from ferroptosis
Bo Yan1, Xun Huang2, Youwei Ai3
1Tianjin Neurological Institute, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin and Ministry of Education, Tianjin Medical University General Hospital, Tianjin 300052, China; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Trends in Endocrinology and Metabolism: TEM
|June 25, 2026
Abstract:
Cells undergo ferroptosis when membrane antioxidant defenses are inhibited, while lipophilic antioxidants can rescue cells from such insults. O'Loughlin et al. show that mTORC1-regulated high-density lipoprotein (HDL) uptake from the culture medium protects cells from ferroptosis.