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Strategy for purification of coagulation factor concentrates
D B Clark1, W N Drohan, S I Miekka
1American Red Cross, Jerome H. Holland Laboratory, Biomedical Sciences, Rockville, MD 20855.
Annals of Clinical and Laboratory Science
|May 1, 1989
Abstract:
Advances in biotechnology are permitting significant changes in traditional plasma fractionation schemes. Increases in product purity, safety, and recovery are possible, and new products are being developed. Applications of technology to the purification of factor IX, factor X, protein C, antithrombin III, thrombin, and fibrin glue are described.