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Updated: Mar 30, 2026

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Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
29.9K
Summary
This case study highlights a 17-year-old diagnosed with major depressive disorder who is a candidate for antidepressant medication. It suggests pediatricians should be comfortable prescribing first-line agents for adolescent depression.
Area of Science:
- Psychiatry
- Pediatrics
- Pharmacology
Background:
- Adolescent depression presents with symptoms like sleep difficulties, dysthymia, and anhedonia.
- Major depressive disorder (MDD) is a common diagnosis in adolescents, often with a family history.
- Adolescents with MDD may benefit from pharmacotherapy in addition to psychotherapy.
Purpose of the Study:
- To illustrate a case of adolescent major depressive disorder.
- To discuss the role of pharmacotherapy in treating adolescent depression.
- To encourage primary care pediatricians to consider prescribing first-line antidepressants for eligible adolescents.
Main Methods:
- A clinical case vignette of a 17-year-old male patient with unipolar major depressive disorder.
- Review of diagnostic criteria for major depressive disorder in adolescents.
- Discussion of pharmacotherapy as a treatment option.
Main Results:
- The patient met diagnostic criteria for unipolar major depressive disorder.
- He had classic symptoms and a strong family history of depression.
- He was deemed a suitable candidate for antidepressant medication initiation.
Conclusions:
- Adolescents with major depressive disorder can be good candidates for antidepressant medication.
- Primary care pediatricians should feel confident in prescribing first-line agents for adolescent depression.
- Collaboration with child and adolescent psychiatry may be beneficial but should not replace primary care comfort with these medications.
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