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Neurogenic lower urinary tract dysfunction in the early disease phase of paediatric multiple sclerosis

Jeroen R Scheepe1, Yu Yi M Wong2, E Daniëlle van Pelt2

  • 1Department of Urology, Erasmus MC, Rotterdam, The Netherlands.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|November 22, 2015
PubMed

Insights

Neurogenic lower urinary tract dysfunction (LUTD) is common in children with multiple sclerosis (MS). Early assessment and treatment are crucial to prevent kidney damage in these young patients.

Area of Science:

  • Pediatric Neurology
  • Urology
  • Neuroimmunology

Background:

  • Neurogenic lower urinary tract dysfunction (LUTD) is a known complication in adult multiple sclerosis (MS).
  • LUTD has not been previously described in pediatric cases of MS.

Purpose of the Study:

  • To determine the prevalence of LUTD in children newly diagnosed with MS.
  • To highlight the importance of early screening for urinary dysfunction in pediatric MS.

Main Methods:

  • Prospective assessment of 24 children with newly diagnosed MS.
  • Evaluation included screening for bladder and bowel problems early after diagnosis.

Main Results:

  • Five out of 24 children (21%) presented with LUTD.
  • One child with LUTD did not report any voiding complaints, indicating asymptomatic presentation.

Conclusions:

  • Pediatric MS frequently involves LUTD, even in asymptomatic cases.
  • Early evaluation and treatment of urinary issues are vital in newly diagnosed pediatric MS patients to prevent upper urinary tract damage.

Keywords:
Paediatricslower urinary tract symptomsmultiple sclerosisneurogenic bladderprevalenceprospective studies

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