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Outbreak in newborns of methicillin-resistant Staphylococcus aureus related to the sequence type 5 Geraldine clone

Camille Leroyer1, Philippe Lehours2, Anne Tristan3

  • 1Department of Infection Control, Groupe Hospitalier Pellegrin, University Hospital, Bordeaux, France.

American Journal of Infection Control
|November 22, 2015
PubMed

Insights

A hospital outbreak of toxic shock syndrome caused by a specific methicillin-resistant Staphylococcus aureus (MRSA) strain was documented. Standard infection control measures were used to manage the spread of this virulent bacteria.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of hospital-acquired infections.
  • Toxic Shock Syndrome (TSS) is a severe, life-threatening illness associated with certain bacterial toxins.

Purpose of the Study:

  • To report the first nosocomial outbreak of TSS-positive MRSA, specifically the sequence type 5 Geraldine clone.
  • To evaluate the effectiveness of standard infection control interventions against this virulent strain.

Main Methods:

  • Case identification and epidemiological investigation of the outbreak.
  • Implementation and monitoring of infection control interventions.
  • Antimicrobial susceptibility testing of the causative MRSA strain.

Main Results:

  • Successful containment of the nosocomial outbreak using standard infection control measures.
  • Identification of the outbreak strain as a specific MRSA clone associated with TSS.
  • Demonstration of the strain's virulence and potential for rapid spread.

Conclusions:

  • Vigilance regarding MRSA antibiotic susceptibilities is crucial, even with standard infection control protocols.
  • The Geraldine clone represents a notable threat in healthcare settings, requiring careful monitoring.
  • Effective infection control strategies remain vital in preventing the dissemination of virulent pathogens.
Keywords:
ControlMethicillin-resistant Staphylococcus aureusNeonatal intensive care unitOutbreakToxic shock syndrome toxin-1Typing

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