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Impact of Universal Decolonization in Intensive Care Units on Rates of Hospital-Acquired Staphylococcus aureus
Charley Ann Nix1, Mary Joyce B Wingler2, Kayla R Stover3
1Department of Pharmacy, University of Mississippi Medical Center, Jackson, MS.
Abstract:
This study evaluated the effectiveness of universal decolonization in intensive care units to decrease hospital-acquired Staphylococcus aureus infections (HA-SAI). HA-SAI (primary endpoint) decreased from 158 patients to 80 patients, infections per 1000 patient days decreased from 5.36 to 2.47, and in-hospital mortality was significantly lower in the post-group (32% vs 16%; p = 0.008). Universal decolonization is a successful way to decrease HA-SAI and reduce in-hospital all-cause mortality amongst adult ICU patients.
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