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Updated: Sep 4, 2026

A Mouse Fetal Skin Model of Scarless Wound Repair
Published on: January 16, 2015
[Mottling: when the skin unveils shock]
Lara Schmid1, Damien Bossel1, Hugo Maroselli1
1Service de médecine interne et des soins intensifs, Hôpital de Nyon, Groupement hospitalier de l'Ouest lémanique, 1260 Nyon.
Abstract:
The morbimortality of sepsis and septic shock is high, and their early diagnosis remains difficult for every physician. While it has long been considered primarily a macrocirculatory disorder, research in recent years has brought to light the central place of microcirculation in sepsis. Using clinical signs, for example on the skin, is an effective way to evaluate microcirculation disorder, making it a useful tool for the diagnosis and monitoring of resuscitation during sepsis. Skin mottling can be used as a prognostic tool, enabling the early identification of patients at high risk of complications.
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