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Updated: Mar 29, 2026

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography
Published on: October 24, 2019
MODEL-BASED ITERATIVE RECONSTRUCTION ENABLES THE EVALUATION OF THIN-SLICE COMPUTED TOMOGRAPHY IMAGES WITHOUT
Marie-Louise Aurumskjöld1, Kristina Ydström2, Anders Tingberg3
1Medical Radiation Physics Malmö, Department of Translational Medicine, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden marie-louise.aurumskjold@med.lu.se.
Abstract:
Computed tomography (CT) is one of the most important modalities in a radiological department. This technique not only produces images that enable radiological reports with high diagnostic confidence, but it may also provide an elevated radiation dose to the patient. The radiation dose can be reduced by using advanced image reconstruction algorithms. This study was performed on a Brilliance iCT, equipped with iDose(4) iterative reconstruction and an iterative model-based reconstruction (IMR) method. The purpose was to investigate the effect of reduced slice thickness combined with an IMR method on image quality compared with standard slice thickness with iDose(4) reconstruction. The results of objective and subjective image quality evaluations showed that a thinner slice combined with IMR can improve the image quality and reduce partial volume artefacts compared with the standard slice thickness with iDose(4) In conclusion, IMR enables reduction of the slice thickness while maintaining or even improving image quality versus iDose(4).
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