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Updated: Jun 29, 2026

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
Published on: December 10, 2014
[QUANTITATIVE INDEXES OF SLOW PERIODICAL VOLUME FLUCTUATIONS INSIDE CRANIA-SPINAL SPACES]
Abstract:
Process of circulatory-metabolic support of brain functioning is based on integration of cerebrovascular and CSF-circulatory systems as well scull mechanics, as united structural-functional system is accompanied by periodic volume--pressure fluctuations inside crania-spinal space. The frequency of them is widely variable (0.03-0.25 Hz), as well as its amplitude (0.3-1.2 of pulse wave value) and they exist in the most of its regions. Results of noninvasive studies of volunteers of groups (18-20 and 40-55 years old), that these fluctuations, reflect the functioning of the mechanism, responsible for brain circulatory metabolic supply, and the evaluation of these quantitative indices by means of spectral analysis with quantization 128 kHz could provide valuable information concerning functional integration of systems, responsible for circulatory-metabolic brain support.
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