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Blood Pressure Variability: Assessment, Prognostic Significance and Management

M Chenniappan

    The Journal of the Association of Physicians of India
    |November 24, 2015
    PubMed

    Insights

    High blood pressure variability (BPV) increases cardiovascular risk. Calcium channel blockers (CCBs), like Amlodipine, are effective in reducing BPV, especially when added to other antihypertensive treatments.

    Area of Science:

    • Cardiology
    • Pharmacology

    Background:

    • Blood pressure variability (BPV) is an emerging cardiovascular risk factor.
    • Elevated BPV strains the cardiovascular system, increasing target organ damage and event risk.

    Purpose of the Study:

    • To evaluate the role of blood pressure variability (BPV) as a cardiovascular risk factor.
    • To investigate the efficacy of calcium channel blockers (CCBs) in reducing BPV.

    Main Methods:

    • Analysis of recent data on antihypertensive drug efficacy.
    • Comparison of BPV reduction across different drug classes, focusing on CCBs.

    Main Results:

    • Calcium channel blockers (CCBs), specifically Amlodipine, demonstrate superior efficacy in reducing BPV compared to other agents.
    • Adding CCBs to existing antihypertensive regimens significantly lowers BPV.

    Conclusions:

    • BPV is a critical factor in cardiovascular risk assessment.
    • CCBs represent a valuable therapeutic option for managing BPV and mitigating cardiovascular risk.

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