Related Experiment Video
Updated: Mar 29, 2026
09:43
Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
3.6K
Lymphomatous Infiltration of Kidneys
The Journal of the Association of Physicians of India
|November 24, 2015
Summary
This case study highlights a rare instance of early kidney involvement in lymphoma, presenting as acute kidney injury (AKI) in a young woman. Despite initial renal function improvement, the patient
Area of Science:
- Nephrology
- Oncology
- Pathology
Background:
- Renal involvement in lymphoma is typically a late-stage, asymptomatic complication.
- Acute kidney injury (AKI) from lymphoma infiltration is exceptionally rare, with an incidence of approximately 0.5%.
Observation:
- A 20-year-old female patient presented with acute kidney injury not requiring dialysis.
- Renal biopsy revealed lymphomatous infiltration as the cause of kidney injury.
Findings:
- The patient's renal function improved following treatment.
- Despite renal recovery, the patient succumbed to central nervous system involvement from lymphoma.
Implications:
- This case underscores the possibility of early and symptomatic renal manifestation of lymphoma, even in young adults.
- Highlights the importance of considering lymphomatous infiltration in the differential diagnosis of AKI, particularly in younger populations.
- Emphasizes the aggressive nature of lymphoma and its potential for multi-systemic, fatal progression despite initial organ-specific treatment success.
Related Concept Videos
01:24Nephrotic Syndrome I : Introduction
970
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
970
01:21External Anatomy of the Kidney
4.7K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
4.7K
01:10Nephrons
8.7K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
8.7K
01:26Nursing Assessment of the Genitourinary System II: Inspection and Palpation
1.3K
The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
1.3K
01:27Acute Pyelonephritis I: Introduction
1.1K
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
1.1K
01:23Detailed Structure and Function of Lymph Nodes
6.2K
Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
6.2K