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Published on: October 31, 2025
Airway Disease and Management in Bronchopulmonary Dysplasia
Raouf S Amin1, Michael J Rutter2
1Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA.
Insights
This article reviews diagnosing and managing airway issues in infants with severe bronchopulmonary dysplasia (BPD). It highlights how respiratory support for premature infants can lead to airway disease, impacting treatment strategies.
Area of Science:
- Neonatology
- Pediatric Pulmonology
- Respiratory Medicine
Background:
- Premature infants often develop respiratory failure due to lung parenchymal and airway diseases.
- Advances in neonatal care increase survival but can lead to chronic lung conditions like bronchopulmonary dysplasia (BPD).
- Airway complications are a significant concern in infants with severe BPD.
Purpose of the Study:
- To provide an overview of the diagnosis and management of airway problems in infants with severe BPD.
- To differentiate management strategies based on whether respiratory failure is parenchymal or airway-driven.
- To discuss tracheotomy indications, timing, and care guidelines for BPD patients.
Main Methods:
- Literature review and synthesis of current clinical practices.
- Analysis of the impact of early continuous airway pressure on BPD incidence.
- Discussion of diagnostic criteria and therapeutic interventions for airway disease in BPD.
Main Results:
- Early continuous airway pressure has positively influenced BPD incidence.
- Management of respiratory failure in BPD requires distinguishing between parenchymal and airway disease.
- Tracheotomy is a potential intervention with specific indications and care requirements.
Conclusions:
- Effective management of airway problems is crucial for infants with severe BPD.
- Tailored treatment strategies are necessary, considering the underlying cause of respiratory failure.
- Tracheotomy guidelines aid in optimizing care for select BPD infants with airway issues.
Abstract:
This article presents an overview of the diagnosis and management of airway problems encountered in infants with severe bronchopulmonary dysplasia (BPD). Respiratory failure in premature infants develops as a result of parenchymal and airway diseases. The survival of increasingly premature infants and the ventilatory support required by premature lungs may result in airway disease. The management of respiratory failure depends on whether it is primarily caused by parenchymal versus airway diseases. Continuous airway pressure early in the neonatal period has favorably changed the incidence of BPD. This article discusses the indications, timing, and guidelines for care of tracheotomy.
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