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Updated: Mar 29, 2026
A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
Published on: August 16, 2017
Constellation Map: Downstream visualization and interpretation of gene set enrichment results
Yan Tan1,2, Felix Wu1, Pablo Tamayo1
1Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Unlabelled:
Gene set enrichment analysis (GSEA) approaches are widely used to identify coordinately regulated genes associated with phenotypes of interest. Here, we present Constellation Map, a tool to visualize and interpret the results when enrichment analyses yield a long list of significantly enriched gene sets. Constellation Map identifies commonalities that explain the enrichment of multiple top-scoring gene sets and maps the relationships between them. Constellation Map can help investigators take full advantage of GSEA and facilitates the biological interpretation of enrichment results.
Availability:
Constellation Map is freely available as a GenePattern module at http://www.genepattern.org.
