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Updated: Mar 29, 2026
09:35
Microcrystallography of Protein Crystals and In Cellulo Diffraction
Published on: July 21, 2017
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Crystallography in the 21st century
1Max Perutz Professor of Molecular Biophysics at the University of Liverpool and Editor-in-Chief of IUCr Journals, Barkla X-ray Laboratory of Biophysics, Institute of Integrative Biology , Life Sciences Building, Liverpool L69 7ZB, UK.
Iucrj
|November 24, 2015
Summary
Crystallography is advancing scientific discovery by overcoming technical limits. Future studies will integrate structure-function-dynamics and explore methods beyond traditional crystal requirements.
Area of Science:
- * Integrative structural biology and biophysics.
- * Advancements in materials science and condensed matter physics.
Background:
- * Crystallography has been pivotal in scientific advancement for a century.
- * Current research pushes the boundaries of traditional crystallographic methods.
Purpose of the Study:
- * To highlight the evolving landscape of crystallography.
- * To emphasize the integration of structure-function-dynamics.
- * To explore novel methods for structure determination.
Main Methods:
- * Overcoming technical and conceptual limitations in structural analysis.
- * Developing non-crystallographic or crystal-free structure determination techniques.
- * Integrating dynamic information with static structural data.
Main Results:
- * Crystallography continues to expand scientific understanding.
- * Structure-function-dynamics is emerging as a key research theme.
- * Progress is being made in obtaining structural information without crystals.
Conclusions:
- * The field of crystallography is dynamic and expanding.
- * Future research will increasingly focus on integrated structure-function-dynamics.
- * Novel techniques will reduce reliance on traditional crystallography.
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