Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Laser Doppler flowmetry in experimental mesenteric vascular occlusion.

K Johansson1, H Ahn, C Kjellström

  • 1Department of Surgery, Norrköping Hospital, Sweden.

International Journal of Microcirculation, Clinical and Experimental
|April 1, 1989
PubMed
Summary

Laser Doppler (LD) and direct current (DC) signals were tested in feline small intestine during blood flow occlusion. LD signals dropped significantly with both arterial and venous occlusion, while DC signals only decreased with venous occlusion.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical practice variation and outcomes regarding single-level posterior approach for degenerative lumbar spondylolisthesis: a Canadian Spine Outcomes Research Network (CSORN) study.

The spine journal : official journal of the North American Spine Society·2025
Same author

Head and neck lymphedema after radiotherapy - Prevalence, changes and associated factors - a prospective observational cohort study.

Oral oncology·2025
Same author

Feasibility and Potential Benefits of Moderate Intensity Cycling in People Living with Lower Limb Lymphedema: A Pilot Randomized Controlled Trial.

Lymphology·2025
Same author

The value of CSF diagnostic and prognostic biomarkers in NMOSD and MOGAD in real-life use.

Multiple sclerosis and related disorders·2025
Same author

In Memoriam: Iwona Swedborg; 1936-2024.

Lymphology·2025
Same author

COVID-19 and global mental health service delivery and financing.

Public health·2022

Area of Science:

  • Physiology
  • Biomedical Engineering
  • Gastroenterology

Background:

  • Assessing intestinal blood flow is crucial for diagnosing and managing gastrointestinal conditions.
  • Laser Doppler (LD) and direct current (DC) signals are optical methods used to measure tissue perfusion.
  • Understanding the behavior of these signals during ischemic events is vital for accurate interpretation.

Purpose of the Study:

  • To evaluate the performance of laser Doppler (LD) and direct current (DC) signals in monitoring feline small intestine blood flow during arterial and venous occlusion.
  • To determine the reliability of these signals in detecting changes in intestinal perfusion under ischemic conditions.

Main Methods:

  • Isolated segments of feline small intestine were subjected to total arterial or venous occlusion.

Related Experiment Videos

  • Laser Doppler (LD) signals, measuring blood flow, and direct current (DC) signals, measuring backscattered light, were recorded.
  • Vascular stalk ligation was performed to simulate prolonged ischemia.

    • Main Results:

    • Following total arterial occlusion, the LD-signal decreased to 16% of control values.
    • Following total venous occlusion, the LD-signal decreased to 29% of control values, and the DC-signal decreased to 78% (p < 0.001).
    • After vascular stalk ligation, a residual LD-signal persisted for 4-6 hours, potentially indicating muscularis layer activity.

    Conclusions:

    • Laser Doppler signals are sensitive to both arterial and venous occlusion in the feline small intestine.
    • Direct current signals are more indicative of venous occlusion and can be affected by tissue congestion.
    • A persistent residual LD-signal during prolonged ischemia may reflect muscularis layer activity, suggesting early intestinal infarction.