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Effective treatments for paronychia caused by oncology pharmacotherapy

Hiroyuki Goto1,2, Shusuke Yoshikawa1, Keita Mori3

  • 1Department of Dermatology, Shizuoka Cancer Center, Shizuoka, Japan.

The Journal of Dermatology
|November 25, 2015
PubMed

Insights

Paronychia, a painful side effect of molecular-targeted cancer drugs, significantly impacts quality of life. Corticosteroid ointment and phenol chemical matricectomy were found to be effective treatments for this condition.

Area of Science:

  • Oncology
  • Dermatology
  • Pharmacology

Background:

  • Cutaneous adverse events are common with molecular-targeted drugs.
  • Paronychia, a nail fold inflammation, causes pain and can disrupt cancer treatment.
  • Effective treatments for severe paronychia are limited.

Purpose of the Study:

  • To evaluate treatment experiences for paronychia in patients undergoing oncology pharmacotherapy.
  • To identify effective interventions for paronychia to maintain quality of life and treatment continuity.

Main Methods:

  • Review of various treatment methods applied to paronychia.
  • Analysis of outcomes for corticosteroid ointment and phenol chemical matricectomy.

Main Results:

  • Various treatments were attempted for paronychia.
  • Corticosteroid ointment and phenol chemical matricectomy showed significant improvement.
  • These treatments helped patients continue their anticancer therapy.

Conclusions:

  • Dermatologists should employ effective treatments for paronychia.
  • Appropriate management of paronychia is crucial for patient quality of life.
  • Timely intervention enables uninterrupted anticancer drug treatment.
Keywords:
combination therapycutaneous adverse eventoncology pharmacotherapyparonychiaquality of life

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