Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA-only Transposons02:57

DNA-only Transposons

18.4K
DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...
18.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sequential Field Therapy in Actinic Keratosis: A Mechanism-Based Rationale for Complementary Treatment Strategies.

Journal of clinical medicine·2026
Same author

Skin Cancer Prevention and Antiaging: Role of Nicotinamide.

International journal of molecular sciences·2026
Same author

Shaping the cognitive reserve: the role of lifelong enrichment and education in the Alzheimer's disease continuum.

Frontiers in aging neuroscience·2026
Same author

Palmoplantar Skin Maceration in a Full-Term Neonate: A Transient and Benign Condition.

International journal of dermatology·2026
Same author

Temporal Programming of Cell-Free Transcription Using Orthogonal Enzyme-Responsive DNA Blockers.

ACS synthetic biology·2026
Same author

RNA-seq sheds light on "who is doing what" in the coral Porites lutea.

Microbiome·2026

Related Experiment Video

Updated: Mar 29, 2026

Designing a Bio-responsive Robot from DNA Origami
13:32

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

23.0K

Enzyme-Operated DNA-Based Nanodevices.

Erica Del Grosso1, Anne-Marie Dallaire2, Alexis Vallée-Bélisle2

  • 1Department of Chemical Science and Technology, University of Rome Tor Vergata , 00133, Rome, Italy.

Nano Letters
|November 25, 2015
PubMed
Summary
This summary is machine-generated.

Researchers developed a new method to control DNA nanodevices using enzymes. This approach expands the range of molecular triggers for DNA nanotechnology, enabling applications like targeted drug delivery.

Keywords:
DNA nanostructuresDNA nanotechnologyenzymesmolecular devices

More Related Videos

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

15.2K
Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

1.7K

Related Experiment Videos

Last Updated: Mar 29, 2026

Designing a Bio-responsive Robot from DNA Origami
13:32

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

23.0K
Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

15.2K
Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

1.7K

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Molecular Biology

Background:

  • DNA-based nanodevices offer versatile and modular platforms for life science and nanomedicine.
  • Current DNA nanodevices have limited molecular stimuli for precise control and regulation.
  • Expanding control mechanisms is crucial for advancing DNA nanotechnology applications.

Purpose of the Study:

  • To demonstrate the rational control and regulation of DNA-based nanodevices using biocatalytic reactions.
  • To showcase the versatility of enzyme-catalyzed reactions as molecular cues for DNA nanodevices.
  • To expand the available molecular stimuli for DNA nanotechnology.

Main Methods:

  • Employed three model DNA-based systems.
  • Utilized three different enzymes from transferase and hydrolase classes.
  • Investigated enzyme-catalyzed reactions to trigger and regulate nanodevice function.

Main Results:

  • Successfully demonstrated enzyme-catalyzed control over DNA-based nanodevices.
  • Showcased the use of enzymes and their substrates as effective molecular cues.
  • Validated the approach across diverse DNA nanodevice systems and enzyme types.

Conclusions:

  • Enzymatic reactions provide a powerful and versatile method for controlling DNA nanodevices.
  • This approach significantly expands the molecular toolbox for DNA nanotechnology.
  • Enables new applications such as enzyme-induced drug delivery and nanostructure assembly.