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Related Experiment Video

Updated: Mar 29, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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Maternal Sepsis and Septic Shock.

Ahmad Chebbo1, Susanna Tan1, Christelle Kassis1

  • 1Department of Medicine, Maricopa Medical Center, 2601 East Roosevelt, Phoenix, AZ 85008, USA.

Critical Care Clinics
|November 25, 2015
PubMed
Summary

Sepsis in pregnancy, a serious condition, has seen its causes evolve since Ignaz Semmelweis identified physician hygiene issues 200 years ago. This review covers current incidence, identification, causes, and management of pregnancy sepsis.

Keywords:
PregnancySepsisSeptic shockSevere sepsis

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Maternal Health

Background:

  • Ignaz Semmelweis identified physician hygiene as a cause of puerperal sepsis 200 years ago.
  • While largely eradicated, understanding sepsis in pregnancy remains critical for maternal health.
  • This review acknowledges Semmelweis's contributions to understanding puerperal infections.

Purpose of the Study:

  • To review the current understanding of sepsis in pregnancy.
  • To highlight the incidence, mortality, and evolving causes of pregnancy-related sepsis.
  • To provide an overview of diagnostic and management strategies.

Main Methods:

  • Literature review of sepsis in pregnancy.
  • Analysis of incidence and mortality data.
  • Examination of diagnostic criteria and scoring systems for sepsis.
  • Review of common causes and infection sites.
  • Summary of current management guidelines.

Main Results:

  • Sepsis in pregnancy presents unique challenges in incidence and mortality.
  • Diagnostic criteria and scoring systems aid in identifying sepsis in pregnant patients.
  • Infections during pregnancy and parturition can lead to sepsis.
  • Effective management guidelines are crucial for improving outcomes.

Conclusions:

  • Sepsis in pregnancy continues to be a significant concern in maternal health.
  • Accurate identification and timely management are essential for reducing mortality.
  • Ongoing research and adherence to guidelines are necessary to combat pregnancy-related sepsis.