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Published on: October 20, 2023
When and how aortic stenosis is first diagnosed: A single-center observational study
Shuo-Ju Chiang1, Masao Daimon2, Sakiko Miyazaki2
1Department of Cardiology, Juntendo University School of Medicine, Tokyo, Japan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei, Medical University, Taipei, Taiwan.
Many aortic stenosis (AS) patients are diagnosed only after symptoms appear, increasing cardiovascular event risk. Early detection through methods like auscultation is crucial for timely intervention and better outcomes in AS management.
Area of Science:
- Cardiology
- Clinical Medicine
- Diagnostic Imaging
Background:
- Aortic stenosis (AS) is linked to cardiovascular events, making early diagnosis critical.
- Limited data exist on symptom status, AS severity at diagnosis, and routine detection methods.
- Understanding diagnosis timing and methods is essential for improving patient outcomes.
Purpose of the Study:
- To investigate the timing and methods of initial diagnosis in patients with aortic stenosis (AS).
- To analyze the characteristics of symptomatic versus asymptomatic AS patients at diagnosis.
- To identify factors influencing AS detection in routine clinical practice.
Main Methods:
- Retrospective enrollment of 198 AS patients diagnosed between 1989 and 2009.
- Analysis of patient symptoms, AS severity, and reasons for hospital visit.
- Categorization into symptomatic and asymptomatic groups based on clinical presentation.
Main Results:
- Over half (58.4%) of AS patients were asymptomatic at diagnosis, detected during routine checkups.
- Systolic murmur on auscultation was the most common initial finding in asymptomatic patients (62%).
- Symptomatic patients exhibited greater AS severity and experienced more cardiac events during follow-up.
Conclusions:
- Approximately 40% of AS patients were diagnosed only after symptom development, indicating potential for latent cardiovascular risks.
- Auscultation is a vital tool for the early diagnosis of aortic stenosis.
- Timely diagnosis and intervention are key to mitigating cardiovascular events in AS patients.
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