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Related Experiment Video

Updated: Mar 29, 2026

Sequential Application of Glass Coverslips to Assess the Compressive Stiffness of the Mouse Lens: Strain and Morphometric Analyses

Sequential Application of Glass Coverslips to Assess the Compressive Stiffness of the Mouse Lens: Strain and Morphometric Analyses

Published on: May 3, 2016

Measuring the cataractous lens.

H John Shammas¹, Maya C Shammas¹

¹From the Department of Ophthalmology (H.J. Shammas), the Keck School of Medicine of the University of Southern California, Los Angeles, and the Shammas Eye Medical Center (H.J. Shammas, M.C. Shammas), Lynwood, California, USA.

Journal of Cataract and Refractive Surgery

|November 26, 2015

Summary

This summary is machine-generated.

Cataract formation increases lens thickness, primarily due to changes in the anterior cortex. This study compared lens dimensions in cataractous eyes versus younger, clear-lens eyes.

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Area of Science:

Ophthalmology
Biomedical Optics
Gerontology

Background:

Lens thickness changes with age and cataract development.
Understanding these changes is crucial for ophthalmic procedures.

Purpose of the Study:

To quantify lens thickness, anterior cortex space, nucleus thickness, and posterior cortex space in cataractous eyes.
To compare these measurements with those in younger individuals with clear lenses.

Main Methods:

Retrospective observational study conducted in a private practice.
Measurements performed using a biometer (Lenstar LS 900).
Comparison between a cataractous group (200 eyes) and a control group (80 eyes).

Main Results:

Cataractous eyes exhibited greater mean lens thickness (4.65 mm) compared to controls (4.09 mm).
Anterior cortex space, nucleus thickness, and posterior cortex space all positively correlated with overall lens thickness.
Lens thickness and its components showed inverse correlations with anterior chamber depth and weak correlations with axial length.

Conclusions:

Lens thickness increases with age and cataract formation.
The increase in lens thickness is predominantly attributed to expansion of the anterior cortex space.