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Multiple Lower Extremity Mononeuropathies by Segmental Schwannomatosis: A Case Report
Na Yeon Kwon1, Hyun-Mi Oh1, Young Jin Ko1
1Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Annals of Rehabilitation Medicine
|November 26, 2015
Summary
This case study presents segmental schwannomatosis, a rare condition of multiple nerve sheath tumors. The patient experienced motor weakness due to multiple mononeuropathies in the lower extremity.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Schwannoma is an encapsulated nerve sheath tumor.
- Segmental schwannomatosis is defined by multiple schwannomas without bilateral vestibular schwannomas.
Purpose of the Study:
- To report a rare case of segmental schwannomatosis presenting with neurologic symptoms.
- To highlight the diagnostic utility of electrodiagnostic studies in such cases.
Main Methods:
- Case presentation of a 46-year-old man with multiple schwannomas.
- Electrodiagnostic studies including nerve conduction studies and electromyography.
- Histopathological examination of nerve tissue.
Main Results:
- Multiple schwannomas were found involving peripheral nerves of the left lower extremity.
- Electrodiagnostic studies confirmed multiple mononeuropathies of the sciatic, common peroneal, tibial, femoral, and superior gluteal nerves.
- Histology confirmed the diagnosis of schwannoma.
Conclusions:
- Segmental schwannomatosis can present with significant neurologic deficits, including motor weakness.
- Electrodiagnostic studies are crucial for identifying and characterizing the extent of nerve involvement in segmental schwannomatosis.
- This case underscores the importance of considering rare nerve sheath tumors in the differential diagnosis of peripheral neuropathies.
