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Published on: February 22, 2019
Complete Genome Sequences of 11 Bordetella pertussis Strains Representing the Pandemic ptxP3 Lineage
Marieke J Bart1, Han G J van der Heide2, Anne Zeddeman1
1Department of Pediatrics, Laboratory of Pediatric Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands Centre for Infectious Diseases Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Abstract:
Pathogen adaptation has contributed to the resurgence of pertussis. To facilitate our understanding of this adaptation we report here 11 completely closed and annotated Bordetella pertussis genomes representing the pandemic ptxP3 lineage. Our analyses included six strains which do not produce the vaccine components pertactin and/or filamentous hemagglutinin.
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