Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biofilms01:29

Biofilms

1.9K
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
1.9K
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

35
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
35
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

878
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
878

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diet and Cognitive Function in Aging: An Individual Participant Data Meta-Analysis from Eight Cohorts in Europe and the United States.

The Journal of nutrition·2026
Same author

AMGST: Adaptive multi-graph convolution and spatiotemporal attention network for traffic forecasting.

PloS one·2026
Same author

A cranberry extract stimulates procollagen I release and expression after UV radiation in a 3D skin model.

International journal of cosmetic science·2026
Same author

The genomic history of Streptococcus mutans from the Mesolithic until modern times.

Genome biology·2026
Same author

Membrane Vesicle-Mediated Delivery of Antibacterial Lipopeptides by <i>Pseudoalteromonas piscicida</i>.

ACS chemical biology·2026
Same author

Performance evaluation of equations of state for typical cryogens two-phase simulation by pseudopotential lattice Boltzmann method.

Physical review. E·2026

Related Experiment Video

Updated: Mar 29, 2026

Bile Salt-induced Biofilm Formation in Enteric Pathogens: Techniques for Identification and Quantification
10:05

Bile Salt-induced Biofilm Formation in Enteric Pathogens: Techniques for Identification and Quantification

Published on: May 6, 2018

13.5K

Cranberry (Vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic Escherichia coli.

Jiadong Sun1, Jannie P J Marais2, Christina Khoo2

  • 1Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.

Journal of Functional Foods
|November 28, 2015
PubMed
Summary
This summary is machine-generated.

American cranberry oligosaccharides, a phenolic-free fraction, significantly reduced uropathogenic Escherichia coli biofilm formation. These findings suggest cranberry

Keywords:
American cranberryEscherichia coliVaccinium macrocarponbiofilmoligosaccharidephenolic

More Related Videos

Methodologies for Studying B. subtilis Biofilms as a Model for Characterizing Small Molecule Biofilm Inhibitors
10:17

Methodologies for Studying B. subtilis Biofilms as a Model for Characterizing Small Molecule Biofilm Inhibitors

Published on: October 9, 2016

16.5K
Adherence of Bacteria to Plant Surfaces Measured in the Laboratory
07:07

Adherence of Bacteria to Plant Surfaces Measured in the Laboratory

Published on: June 19, 2018

13.5K

Related Experiment Videos

Last Updated: Mar 29, 2026

Bile Salt-induced Biofilm Formation in Enteric Pathogens: Techniques for Identification and Quantification
10:05

Bile Salt-induced Biofilm Formation in Enteric Pathogens: Techniques for Identification and Quantification

Published on: May 6, 2018

13.5K
Methodologies for Studying B. subtilis Biofilms as a Model for Characterizing Small Molecule Biofilm Inhibitors
10:17

Methodologies for Studying B. subtilis Biofilms as a Model for Characterizing Small Molecule Biofilm Inhibitors

Published on: October 9, 2016

16.5K
Adherence of Bacteria to Plant Surfaces Measured in the Laboratory
07:07

Adherence of Bacteria to Plant Surfaces Measured in the Laboratory

Published on: June 19, 2018

13.5K

Area of Science:

  • Food Science
  • Microbiology
  • Biochemistry

Background:

  • American cranberry (Vaccinium macrocarpon) is known for preventing urinary tract infections (UTIs).
  • Previous research focused on cranberry's phenolic compounds for UTI prevention.
  • The role of non-phenolic components remains less understood.

Purpose of the Study:

  • To investigate the anti-biofilm properties of a phenolic-free carbohydrate fraction from American cranberry.
  • To determine if cranberry oligosaccharides contribute to UTI prevention.

Main Methods:

  • A phenolic-free carbohydrate fraction (cranf1b-F2) was isolated using chromatography.
  • Oligosaccharide structure was analyzed using MALDI-TOF-MS, GC-MS, and NMR.
  • Antimicrobial assays tested the fraction's effect on Escherichia coli biofilm formation and growth.

Main Results:

  • The cranf1b-F2 fraction consisted mainly of xyloglucan and arabinan oligosaccharides.
  • cranf1b-F2 significantly reduced uropathogenic E. coli CFT073 biofilm production by over 50% without affecting bacterial growth.
  • Non-pathogenic E. coli MG1655 biofilm formation was inhibited up to 60% in a dose-dependent manner.

Conclusions:

  • Cranberry oligosaccharides possess anti-biofilm activity against E. coli.
  • These oligosaccharides may contribute to the overall UTI-preventive effects of American cranberry, alongside phenolic compounds.